The innovation and entrepreneurship education puts forward the internal requirements for the change of learning space, the research has put forward the trend of the change of learning space, and the practice has also shown the universality and trend of the change of learning space, but the change of learning space in the world is in the initial stage of exploration as a whole. Based on the correlation analysis of the core elements such as space, technology, teaching method and learning

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... , this paper puts forward the design framework of active learning space, and presents different forms of space cases based on the demand of innovation and entrepreneurship education, which can provide practical reference for the construction of active learning space in similar universities. In the future, it is also necessary to explore the internal mechanism and manifestation of the influence of learning space on the cultivation of innovative talents, summarize the application mode of learning space for innovation and entrepreneurship education, and promote the continuous deepening of innovation and entrepreneurship education.