Preserved autonomic regulation in patients undergoing transcatheter aortic valve implantation (TAVI) – a prospective, comparative study

Beatrice Retzlaff, Niels Wessel, Maik Riedl, Andrej Gapelyuk, Hagen Malberg, Nina Bauernschmitt, Jürgen Kurths, Georg Bretthauer, Robert Bauernschmitt
2011 Biomedical Engineering  
Heart rate and blood pressure variability as well as baroreflex sensitivity (BRS) lead to additional insights on the patients' prognosis after cardiovascular events. The following study was performed to assess the differences in the postoperative recovery of the autonomic regulation after transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR). Fifty-eight consecutive patients were enrolled in a prospective study; 24 underwent TAVI and 34 SAVR. BRS was
more » ... AVR. BRS was calculated according to the Dual Sequence Method, heart rate variability (HRV) was evaluated using standard linear as well as nonlinear parameters. HRV and BRS parameters were reduced after surgery in patients with SAVR only (meanNN: p-0.001, sdNN: p-0.05, Shannon: p-0.01, BRS: p-0.01), while these indexes were preserved in patients after TAVI. Simultaneously, an increased complexity of blood pressure (BP) in SAVR patients (fw-Shannon: p-0.001, fwRenyi4: p-0.001), but not in TAVI patients was recorded. In this study we were able to demonstrate for the first time that, in contrast to patients undergoing conventional open surgery, there are fewer alterations of the cardiovascular autonomic system in patients with TAVI.
doi:10.1515/bmt.2011.017 pmid:21823996 fatcat:budrantaobhlnjrv767i2vdbyq