This paper describes the growth response of the developmental stages of hybrid cat ish resulting rom the crossing of Heterobranchus bidorsalis (male) and Clarias gariepinus (female), fed with different feed rations. Hatchlings of the hybrid catfish were cultured in plastic aquaria set up at the fish hatchery complex, Nnamdi Azikiwe University, Awka. The hatchlings were fed and observed for 91 days. Different food items such as artificially compounded feed, zooplankton / live organisms Moina sp

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... nd Brachionus sp, and a mixture of zooplankton (Moina sp and Brachionus sp) and artificially compounded feed were administered. The mixture gave the best result with a mean weight o 7 92g ± 2.73g fo lowed by those fed Moina sp (1.93g ± 0.27) and Brachionus sp (1.80g ± 0.32) respectively. Hatchlings fed only artificially compounded feed exhibited the poorest growth. A mixture of live food organisms and art cially compounded feed is thus recommended for better growth response of catfish hybrid, (H. bidorsalis ♂ x C. gariepinus ♀).