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Computational approach for selection of epitope-based dengue vaccine targets
Vietnam Journal of Biotechnology
High antigenic variability in the envelope (E) protein of different virus strains has been a major obstacle in designing effective vaccines for Dengue virus (DENV). To maintain their biological function, some parts of viral proteins remain stable during evolution thus one possible approach to solve this problem is to recognize specific regions within different protein sequences of E that have the tendency to stay constant through evolution. These regions may possess some special attributes todoi:10.15625/1811-4989/14/4/12244 fatcat:474scecuynh2fab5szw77tq7wa