Inability of Lyapunov Exponents to Predict Epileptic Seizures

Ying-Cheng Lai, Mary Ann F. Harrison, Mark G. Frei, Ivan Osorio
2003 Physical Review Letters  
It has been claimed that Lyapunov exponents computed from electroencephalogram or electrocorticogram (ECoG) time series are useful for early prediction of epileptic seizures. We show, by utilizing a paradigmatic chaotic system, that there are two major obstacles that can fundamentally hinder the predictive power of Lyapunov exponents computed from time series: finite-time statistical fluctuations and noise. A case study with an ECoG signal recorded from a patient with epilepsy is presented.
doi:10.1103/physrevlett.91.068102 pmid:12935113 fatcat:7qemfd3pzfh73lqfhbhsctqhcm