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A One-Pot Divergent Sequence to Pyrazole and Quinoline Derivatives
The hydroxy-pyrazole and 3-hydroxy-oxindole motifs have been utilised in several pharma and agrochemical leads but are distinctly underrepresented in the scientific literature due to the limited routes of preparation. We have developed a one-pot procedure for their synthesis starting from simple isatins. The method employs cheap and easy-to-handle building blocks and allows easy isolation.doi:10.3390/molecules25092160 pmid:32380725 fatcat:rywodblnbjhwhmfnzo7x5b35ja