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Lipoprotein-Associated Phospholipase A2 Is an Independent Marker for Coronary Endothelial Dysfunction in Humans
Arteriosclerosis, Thrombosis and Vascular Biology
Objective-The purpose of the current study was to determine whether lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) is associated with coronary endothelial dysfunction and is a predictor of endothelial dysfunction in humans. Methods and Results-Patients (172) with no significant coronary artery disease (Ͻ30% stenosis) undergoing assessment of coronary endothelial function were studied. Endothelial function was assessed by the change in coronary blood flow and coronary artery diameter indoi:10.1161/01.atv.0000191655.87296.ab pmid:16239595 fatcat:62l6v2p5njcrzgo6e2dr2grgvm