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Genetic Contribution of Endometriosis to the Risk of Developing Hormone-Related Cancers
2021
International Journal of Molecular Sciences
Endometriosis is a common gynecological disorder that has been associated with endometrial, breast and epithelial ovarian cancers in epidemiological studies. Since complex diseases are a result of multiple environmental and genetic factors, we hypothesized that the biological mechanism underlying their comorbidity might be explained, at least in part, by shared genetics. To assess their potential genetic relationship, we performed a two-sample mendelian randomization (2SMR) analysis on results
doi:10.3390/ijms22116083
pmid:34199930
pmcid:PMC8200110
fatcat:7wor3prohrhkdk52efhp73ekbe