A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
The de novo emergence of new transcripts has been well documented through genomic analyses. However, a functional analysis, especially of very young protein coding genes, is still largely lacking. Here we focus on three loci that have evolved from previously intergenic sequences in the house mouse (Mus musculus) and are not present in its closest relatives. We have obtained knockouts and analyzed their phenotypes, including a deep transcriptomic analysis, based on a dedicated power analysis. Wedoi:10.1101/510214 fatcat:7pbxehm7fnaxdggfyexq7tyvdi