Acrokeratosis Verruciformis of Hopf: A Rare Case Report

N.T. Chaitanya
2020 Zenodo  
Acrokeratosis verruciformis (AKV) of Hopf is a rare autosomal dominant genodermatosis characterised by multiple hyperkeratotic, skin-coloured, verrucous papules on hands and feet. We present a 4-year-old female with itchy lesions around the right ankle since the age of 3 months without any family history of AKV. Clinical investigation showed multiple hyperpigmented, hyperkeratotic grouped papules and histopathology showed hyperkeratosis, acanthosis, papillomatosis with church-spire like
more » ... -spire like elevation of the epidermis without signs of dyskeratosis and mild lymphocytic infiltrate in the dermis. Treatment with 0.05% topical tretinoin showed improvement within two weeks.
doi:10.5281/zenodo.3980535 fatcat:6nuvx6nvpffpfhyyzhis5qwkt4