Metastatic Adrenocortical Carcinoma Treated with Sunitinib: A Case Report

Jeong-Ok Lee, Keun-Wook Lee, Chung-Jong Kim, Yu Jung Kim, Hee Eun Lee, Haeryoung Kim, Jee Hyun Kim, Soo-Mee Bang, Jae-Sung Kim, Jong Seok Lee
2009 Japanese Journal of Clinical Oncology  
Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis. Palliative chemotherapy can be considered in patients with metastatic disease. Although mitotane-or cisplatin-based chemotherapy regimens are widely used, the effects of these agents have been limited. We have experienced a case that showed a partial response with sunitinib after failure of mitotane-based cytotoxic chemotherapy. The clinical benefit from sunitinib persisted 7.5 months in this case. To our knowledge, this
more » ... the first reported case showing the effects of sunitinib on metastatic ACC.
doi:10.1093/jjco/hyn146 pmid:19168875 fatcat:lvabvpyi4vdujagmdcp43r2yvy