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Chitosan Increases α6 Integrinhigh/CD71highHuman Keratinocyte Transit-Amplifying Cell Population
Biomolecules & Therapeutics
Glycosaminoglycans (GAGs) and chitosan have been used as matrix materials to support the dermal part of skin equivalent which is used for both pharmacological and toxicological evaluations of drugs potentially used for dermatological diseases. However, their biological roles of GAGs and chitosan in the skin equivalent are still unknown. In the present study, we evaluated whether GAGs and chitosan directly affect keratinocyte stem cells (KSCs) and their transit-amplifying cells (TA cells). Amongdoi:10.4062/biomolther.2010.18.3.280 fatcat:yfty33qp65c2vhpnqjkcy3s26y