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In this article, we described the synthesis of various derivatives of 5-Chloroisatin by the action of halogenated mono channels, benzyl chloride and methyl iodide under the conditions of phase transfer catalysis (PTC), which are widely used as a starting material for the synthesis of heterocyclic compounds and as substrates for the synthesis of drugs. In order to multiply the family heterocyclic compound from 5-Chloro-1H-indole-2,3-dione using the N-alkylation reaction which is answered in thefatcat:ldzounr2sbagnbtefog4a64u6q