Comparative Evaluation of performance of Mannheim Peritonitis Index (MPI) and Multiple Organ Failure Score in Patients with Peritonitis ORIGINAL RESEARCH

Salamat Khan, V Singh
Secondary bacterial peritonitis is a life threatening condition if not well managed. It is associated with high morbidity and mortality. Early stratification by scoring system will allow in predicting the possible outcome and providing more critical care services to the serious patients. Aim: This study was done to evaluate the performance of Mannheim Peritonitis Index (MPI) score and MOF score in patients with secondary peritonitis. Material and Methods: This is a prospective,observational
more » ... uation of MPI and MOF score which was conducted on 105 consecutive patients of peritonitis who were admitted in our institution and underwent appropriate surgical treatment. Patient's characteristics, clinical, laboratory findings, operative findings and postoperative outcome were noted. Results: Overall, mortality was 11.4%.The highest prediction of mortality rate of 85.7% was at MPI score of>27.The prediction of mortality of MOF score was 80% (12/15). Non-survivors had mean score of MPI and MOF was 28.50± 3.6and 3.46 ±2.19 respectively whereas survivors had mean MPI and MOF of 17.48±5.8 and 0.82 ±0.115 respectively. The Score sensitivity of mortality were 100% and 83.33% for MPI score >20 and MOF score respectively. The lower sensitivity of MOF score was due to death of some cases above 50 years of age without organ failure. These deaths were due to sudden cardio-respiratory arrest. Conclusion: Increasing MPI and MOF score were associated with poor outcome. Both MPI and MOF were good predictors of mortality in cases of peritonitis. However; MPI scoring system is better (sensitivity 100% Vs. 83.3%) predictor of mortality than MOF score.