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We have created and validated a conceptual framework for the core physiology concept of "cell membrane." The conceptual framework is composed of 27 items arranged in a hierarchy that is, in some instances, four levels deep. We have validated it with input from faculty who teach at a wide variety of institutional types. All items making up the framework were deemed essential to moderately important. However, some of the main ideas were clearly judged to be more important than others.doi:10.1152/advan.00051.2019 pmid:31361151 fatcat:kbwkml6akng3dc7bxf6dmfhvom