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Fast diagnosis of Avian Influenza is a prerequisite for confining outbreaks. Diagnosis implies the differentiation of virulent and non-virulent Avian Influenza virus. After starting with PCR screening for matrix protein followed by identifying the presence of H5 and N1 genes, the diagnosis methodology within Romanian Institute for Diagnosis and Animal Health has moved to rapid molecular tests for detecting the virulent and nonvirulent strains. During October-December 2005 over 3400 biologicaldoi:10.2298/bah0701411z fatcat:cw5sjdlll5epneusdbocpxcc5u