We consider supersymmetric SO(10) grand unification where the unified gauge group can break to the Standard Model gauge group through different chains. The breaking of SO(10) necessarily involves the reduction of the rank, and consequent generation of non-universal supersymmetry breaking scalar mass terms. We derive squark and slepton mass relations, taking into account these non-universal contributions to the sfermion masses, which can help distinguish between the different chains through

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... the SO(10) gauge group breaks to the Standard Model gauge group. We then study some implications of these non-universal supersymmetry breaking scalar masses for the low energy phenomenology.