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Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based method
2007
Nucleic Acids Research
2007. Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based method. Nucleic Acids Research 35(11): e81. Published Version ABSTRACT The C 2 H 2 zinc finger is the most commonly utilized framework for engineering DNA-binding domains with novel specificities. Many different selection strategies have been developed to identify individual fingers that possess a particular DNA-binding specificity from a randomized library. In these experiments,
doi:10.1093/nar/gkm385
pmid:17537811
pmcid:PMC1920264
fatcat:e75ex6yxbffunlbvsqo5fgfom4