Snakehead fish, Haruan (Channa striata): Emerging potential for nutraceuticals, active pharmaceutical ingredients (API) and biomedical applications
ABDULL MANAN MAT JAIS, AHMAD KHUSAIRI AZEMI, MOHAMMAD HAFIZ ABDUL RAHIM, SADEGH ABEDI, IRMA IZANI MOHAMAD ISA, MEERA KUPPUSAMY, TARITA TAIB, M. AMINUR RAHMAN
Bangladesh Journal of Fisheries
This is a collaborative effort between Malaysia and Bangladesh to introduce and promote thestriped-snakehead Haruan Channa striata (Bloch 1793) or Shol in Bangladesh as natural product resources forfood, cosmetic and pharmaceutical industry. The objective is to involve up-scaling biotechnological activity toprepare by-product(s) utilizing every-parts of the fish. The project will reduce organic waste, generate higherrevenue and improve quality-life of farmers. Here is a case-study as a
... , reviewing outcome of adrug discovery R & D on the species in Malaysia since 1985 where Haruan, a good source of protein, theundisputed oral traditional medicine inducing quick recovery for ladies after giving birth. Accordingly, stockidentification and environmental physiology data of this indigenous species were obtained: inhabiting warm,clean, shallow slow-running or stagnant water with aquatic-flora or dead-wood as hiding/resting placeambushing preys. This information is key to a sustainable commercial-scale aquaculture Haruan Agro-Pharmaceutical Industry (HAPI); comprising pre-harvest; and extended to post-harvest activities. Theestablishment is to maintaining and sustaining the unique biochemistry reflecting carnivorous behaviorconsuming other fishes, amphibians and reptiles. The fish contains high-protein (>60 %), low-fat (<3 %)and comprehensive dietary minerals with a good amino acid profile, high in Glycine and fatty acid with ?-6(Arachidonic Acid), ?-3 (Docasahexaenoic Acid or DHA), albumin and cyclic-peptide N-arachidonylglycine@ NAGly. Hence, a proprietary standard operating procedure as a technology had been established, andsuccessfully performed for extracting the biochemistry through a Pressurized In-Water Extraction (PIWE).The extract is termed as Haruan Manan (HM). However, actual protocol is a trade-secret. It is a bioactive,key ingredient in every Haruan Biomedical Product (HBP) inducing wound-healing, reducing-pain, treatinginflammation and inhibiting growth of pathogenic bacteria (including Staphylococcus aureus and Helicobacterpylori). These four physiological steps to healing, curing and treating are demonstrated by our first product:Haruan Cream containing 5% of the HM for skin disease, eczema. HM is a signature, Active PharmaceuticalIngredient (API); and we are discussing, demonstrating and high-lighting potential of C. striata as functionalfood,nutraceuticals and API.