Obstructive Sleep Apnea Is Frequent in Patients with Hypertensive Intracerebral Hemorrhage and Is Related to Perihematoma Edema

Octavio M. Pontes-Neto, Regina M.F. Fernandes, Heidi H. Sander, Larissa A.T. da Silva, Débora C. Mariano, Fernando Nobre, Gustavo Simão, Draulio B. de Araujo, Antonio C. dos Santos, João P. Leite
2010 Cerebrovascular Diseases  
Obstructive sleep apnea (OSA) is related to increased systemic inflammation and arterial hypertension. We hypothesize that OSA is frequent in patients with acute hypertensive intracerebral hemorrhage (ICH) and is related to the perihematoma edema. Methods: Thirty-two non-comatose patients with a hypertensive ICH underwent polysomnography in the acute phase. Perihematoma edema volume was measured on CT scans at admission, after 24 h (early control) and after 4-5 days (late control). The Spearman
more » ... coefficient (r s ) was used for correlations. Results: OSA occurred in 19 (59.4%) patients. The apnea-hypopnea index was correlated with relative edema at admission CT (r s = 0.40; p = 0.031), early CT (r s = 0.46; p = 0.011) and at late CT (r s = 0.59; p = 0.006). Conclusions: OSA is highly frequent during the acute phase of hypertensive ICH and is related to perihematoma edema.
doi:10.1159/000255972 pmid:19893310 fatcat:nlhcwfljb5fprn6gmzrk5323je