Fractional-Order Closed-Loop Model Reference Adaptive Control for Anesthesia

Gerardo Navarro-Guerrero, Yu Tang
2018 Algorithms  
The design of a fractional-order closed-loop model reference adaptive control (FOCMRAC) for anesthesia based on a fractional-order model (FOM) is proposed in the paper. This proposed model gets around many difficulties, namely, unknown parameters, lack of state measurement, inter and intra-patient variability, and variable time-delay, encountered in controller designs based on the PK/PD model commonly used for control of anesthesia, and allows to design a simple adaptive controller based on the
more » ... Lyapunov analysis. Simulations illustrate the effectiveness and robustness of the proposed control.
doi:10.3390/a11070106 fatcat:nteeypukrndtla7n24qp5aviay