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CFTR activity is enhanced by the novel corrector GLPG2222, given with and without ivacaftor in two randomized trials
2019
Journal of Cystic Fibrosis
Several treatment approaches in cystic fibrosis (CF) aim to correct CF transmembrane conductance regulator (CFTR) function; the efficacy of each approach is dependent on the mutation(s) present. A need remains for more effective treatments to correct functional deficits caused by the F508del mutation.
doi:10.1016/j.jcf.2019.04.014
pmid:31056441
fatcat:6nar6hl5grhzdbu3uayunrq5ma