The Maximum Caliber Variational Principle for Nonequilibria

Kingshuk Ghosh, Purushottam D. Dixit, Luca Agozzino, Ken A. Dill
2020 Annual review of physical chemistry (Print)  
Ever since Clausius in 1865 and Boltzmann in 1877, the concepts of entropy and of its maximization have been the foundations for predicting how material equilibria derive from microscopic properties. But, despite much work, there has been no equally satisfactory general variational principle for nonequilibrium situations. However, in 1980, a new avenue was opened by E.T. Jaynes and by Shore and Johnson. We review here maximum caliber, which is a maximum-entropy-like principle that can infer
more » ... ributions of flows over pathways, given dynamical constraints. This approach is providing new insights, particularly into few-particle complex systems, such as gene circuits, protein conformational reaction coordinates, network traffic, bird flocking, cell motility, and neuronal firing. Expected final online publication date for the Annual Review of Physical Chemistry, Volume 71 is April 20, 2020. Please see for revised estimates.
doi:10.1146/annurev-physchem-071119-040206 pmid:32075515 pmcid:PMC9827727 fatcat:jlydees3ebg2tmzomy2c3hkvae