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Extreme warming at the end-Permian induced profound changes in marine biogeochemical cycling and animal habitability, leading to the largest extinction in Earth's history. However, a causal mechanism for the extinction that explains the different proxy evidence has yet to be found. By combining recent modeling developments with global and local redox observations, we show that a temperature-driven increase in microbial respiration can reconcile reconstructions of the spatial distribution ofdoi:10.21203/rs.3.rs-80350/v1 fatcat:jqpuxanq3ba2xfouv5qean33ri