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This paper aims at analyzing the expression and significance of the brain-derived neurotrophic factor (BDNF) in colon cancer cells. The expressions of BDNF have been detected in both of the colon cancer cell lines and the normal intestinal epithelial cell lines. The Colon cancer cell line has a high expression of the Trk B while it has no expression for the BDNF. The normal intestinal epithelial cell line HIEC has no expression for BDNF and low expression for Trk B. The proliferation rate bydoi:10.14704/nq.2018.16.6.1665 fatcat:7b242vsjezhf5nard7hbbcelwe