THE DETERMINATION OF MONOAMINE OXIDASE ACTIVITY [chapter]

H. SOEP
1962 Enzymes in Clinical Chemistry  
DEFINITION OF AMINE OXIDASES According to Zeller 1 • 2 , the oxidative deamination of amines consists in the substitution of carbonyl groups for aliphatic amino groups. The enzymes which catalyse this oxidative deamination are usually called amine oxidases or dehydrogenases. The amine oxidases are divided in two main groups: the first group consisting ofthose which attack a-methylamines (e.g. amphetamine), and the second group of those which do not do so. Two categories are distinguishable in
more » ... e second group: those enzymes which are inhibited in the presence of 10-3 M semicarbazide, and those which are not. The monoamine oxidases belong to this last group of " I0-3 M semicarbazide resistant oxidases ". The different groups of amine oxidases are listed in Table ] . Unauthenticated Download Date | 7/25/18 4:55 PM
doi:10.1016/b978-0-08-021157-2.50017-1 fatcat:k5j4bphawzhvfbeltkbnt2p6qa