Masters Thesis defended at the University of Sao Paulo

Leonardo De Oliveira Martins
2017 Figshare  
This project aimed the creation of a simulation environment for viral gene sequences, with special attention to HIV-1 genes, for the generation of simulated sequences within a known selective scenario [33]. An algorithm was created to ascribe the fitness of each sequence based on its similarity to the ancestral sequence. Several estimates of effective population size and test statistics for detecting selection based on sequence data and on phylogenies were compared under several selective
more » ... ral selective models and population sizes, in order to stablish the power of each estimate.
doi:10.6084/m9.figshare.5144686.v1 fatcat:kvp4s6aysvhjnph3ryvelnwyd4