Relationships between cotransducible plasmids in Staphylococcus aureus

S Iordănescu
1977 Journal of Bacteriology  
Cotransduction of two or even three plasmids was -observed when a Staphylococcus aureus strain, carrying five distinct, compatible plasmids, was used as donor. An active host recombination system did not seem to be indispensable for plasmid cotransduction, since RecA+ and RecAdonors gave similar cotransduction frequencies. Analysis of plasmids carried by cotransductant clones demonstrated that a genetic interaction can take place between cotransduced plasmids, leading to new plasmids. Some of
more » ... plasmids. Some of the properties of these new plasmids are discussed. Another set of experiments tested the ability of a cotransducible plasmid to allow a significant degree ofmultiplication of a temperature-sensitive plasmid at restrictive temperature. In an attempt to explain the results obtained, a working hypothesis suggesting a transient and reversible association of cotransducible plasmids is presented. on May 9, 2020 by guest http://jb.asm.org/ Downloaded from mid.
doi:10.1128/jb.129.1.71-75.1977 fatcat:et2syk4oqrcb3omvocw2thskni