Study of the antimicrobial activity of phytoointment for treatment of mechanical damages of dairy tissue

Zuikina S, Vyshnevska L, Silaeva L
2019 Zenodo  
Introduction. One of the common pathologies found in gynaecological practice is cracking nipples, which represent the rupture of an external sensitive epidermis due to its mechanical damage. Cracks have different shapes (straight and stellar), as well as different depths (superficial and deep). The nature of cracks is quite diverse: poor quality personal care products or non-compliance with personal hygiene rules, low-quality gels and cosmetics, improper breastfeeding, vitamin A and E
more » ... n A and E deficiency, early use of hormonal contraceptives and other medicines, tanning bed, improperly selected linen and other. Diagnosis is performed only when there are complaints, namely: when the nipple swells, blushing, pain and heaviness in the chest are felt. The treatment is prescribed by the doctor depending on the duration of the disease and its severity. If the disease lasts up to three days, then wound healing, antiseptic and palliative drugs are prescribed. If the disease lasts more than three days, then antibiotic therapy is added to these agents, as there is a secondary infection. In such cases, the breastfeeding of the baby stops.Taking into account the above, the composition of the soft dosage form for use in gynaecology, which has reparative, wound healing action, was developed. Ointment under the conventional name "Phytolan" contains in its composition vegetable oils: amaranth, sea buckthorn, parsley leaves, melaleuca and lanolin anhydrous as the basis. The aim of the research was comparative study of the spectrum and level of antimicrobial activity in vitro ointment "Phytolan", the comparator preparation - the analogue by the action of the cream "Mama care" and specimens containing ointment base - anhydrous lanolin and a separate phytooil in a concentration of 10%. Material&methods. As test strains we took standard strains from the American standard collection of microorganisms: Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 9027, Bacillus [...]
doi:10.5281/zenodo.3572560 fatcat:divue3r7evemnmyymdbinnfraa