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GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between Health and Disease
2021
International Journal of Molecular Sciences
GPCRs arguably represent the most effective current therapeutic targets for a plethora of diseases. GPCRs also possess a pivotal role in the regulation of the physiological balance between healthy and pathological conditions; thus, their importance in systems biology cannot be underestimated. The molecular diversity of GPCR signaling systems is likely to be closely associated with disease-associated changes in organismal tissue complexity and compartmentalization, thus enabling a nuanced
doi:10.3390/ijms222413387
pmid:34948182
pmcid:PMC8708147
fatcat:kn7hrmgxojg6vp7u57edejuoh4