Classification of the dermal-epidermal junction using in-vivo confocal microscopy

J. Robic, B. Perret, A. Nkengne, M. Couprie, H. Talbot
2017 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017)  
Reflectance confocal microscopy (RCM) is a powerful tool to visualize the skin layers at cellular resolution. The dermalepidermal junction (DEJ) is a thin complex 3D structure. It appears as a low-contrasted structure in confocal en-face sections, which is difficult to recognize visually, leading to uncertainty in the classification. In this article, we propose an automated method for segmenting the DEJ with reduced uncertainty. The proposed approach relies on a 3D Conditional Random Field to
more » ... del the skin biological properties and impose regularization constraints. We improve the restitution of the epidermal and dermal labels while reducing the thickness of the uncertainty area in a coherent biological way from 16.9 µm (ground-truth) to 10.3 µm.
doi:10.1109/isbi.2017.7950513 dblp:conf/isbi/RobicPNCT17 fatcat:f7zo64t74fbqbnznjukpev2qvi