Type 2 diabetes mellitus and thyroid disease: a two-sided analysis

S. Sotak, M. Felsoci, I. Lazurova
2018 Bratislava Medical Journal  
AIM OF THE STUDY: To assess the prevalence of thyroid diseases in patients with type 2 diabetes mellitus (T2DM) in comparison with normal population; to determine prevalence of T2DM in patients with thyroid diseases. MATERIALS AND METHODS: First group consisted of 60 patients with T2DM without previous history of thyroid disease. Second group consisted of 60 patients with thyroid disease without any previously known impairment of glucose metabolism. Control group (CG) included 100 subjects who
more » ... ad no previous history of thyroid disease or glucose metabolism impairment. Blood tests were performed to evaluate thyroid and glucose metabolism parameters. RESULTS: We found a signifi cantly higher prevalence of thyroid diseases in patients with T2DM when compared to CG. Patients with T2DM showed to have higher serum levels of free triiodothyronine (fT 3 ), thyroid-stimulating hormone (TSH) and anti-thyroid peroxidase (anti-TPO) autoantibodies. We found no statistical signifi cance in prevalence of T2DM in patients with thyroid diseases and CG. Among parameters of glucose metabolism, there were only higher fasting glucose levels in patients with hyperthyroidism and autoimmune thyroid disease (AITD). CONCLUSIONS: Patients with T2DM showed to have higher prevalence of AITD and primary hypothyroidism. We did not fi nd higher prevalence of T2DM in patients with thyroid diseases (Tab. 3, Ref. 29). Text in PDF www.elis.sk.
doi:10.4149/bll_2018_067 pmid:29947236 fatcat:y7elhmqfbzh7lm5ulyjh2txhsu