Facilitating Osteogensis of Mineral Trioxide Aggregate And Biodentine by Autogenous Bone Marrow. (experimental Study on Rabbit)
The Journal of The University of Duhok
Maxillofacial surgery employs several surgical procedures in soft and hard tissues. When hard tissues are involved, for instance, periapical surgery, cyst enucleation, tumor resection, preprosthetic surgery, when the large bony defect remaining intact it is necessary to replace by bone grafting. An in vivo and vitro studies has also shown that Mineral trioxide aggregate (MTA) and biodentine promotes both dental and bony regeneration in pulp and periradicular tissues and both have excellent
... have excellent biocompatibility. Materials and Methods: 20 rabbits of both sexes were enrolled in this study, three monocortical defects were created on Mandible, one considered as control and the others implanted with MTA and biodentine, on tibia, three monocortical defects were created on the same animal. Post-operative follow up date 7,14,21and 28 Days. C.T. scan was used as parameter for bone density measurement. Results: showed that non-significant difference at Day7 and14 in Mandible and significant at Day21 and 28 compared to control, While nonsignificant at Day 7 in Tibia and significant at 14 and21 post-operatively with highly significant at Day28 compared to control. Conclusion: MTA and biodentine have effect on process of osteogenesis and will facilitating when it implanted with Bone marrow.