A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf
.
AGEs induce oxidative stress and activate protein kinase C-βII in neonatal mesangial cells
2000
AJP - Renal Physiology
Scivittaro, Vincenzo, Michael B. Ganz, and Miriam F. Weiss. AGEs induce oxidative stress and activate protein kinase C- II in neonatal mesangial cells. Am J Physiol Renal Physiol 278: F676-F683, 2000.-Increased activation of specific protein kinase C (PKC) isoforms and increased nonenzymatic glycation of intracellular and extracellular proteins [the accumulation of advanced glycation end products (AGEs)] are major mechanistic pathways implicated in the pathogenesis of diabetic complications.
doi:10.1152/ajprenal.2000.278.4.f676
pmid:10751230
fatcat:thzkbrahgfg5tbsxrlvytg52ty