A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf
.
Gain and Loss of Function mutations in biological chemical reaction networks: a mathematical model with application to colorectal cancer cells
[article]
2020
arXiv
pre-print
This paper studies a system of Ordinary Differential Equations modeling a chemical reaction network and derives from it a simulation tool mimicking Loss of Function and Gain of Function mutations found in cancer cells. More specifically, from a theoretical perspective, our approach focuses on the determination of moiety conservation laws for the system and their relation with the corresponding stoichiometric surfaces. Then we show that Loss of Function mutations can be implemented in the model
arXiv:2004.02632v1
fatcat:ucb7fopnirb5lgmnlom44jqcri