Comparative Evaluation On The Efficacy Of Embryonated Chicken Egg Adapted And Tissue Culture Pigeon Pox Vaccines Against The Local Virulent Strain
Journal of Applied Veterinary Sciences
A total of 150 pigeons of 45 days old was used and divided into three groups; the first one was vaccinated with tissue culture adapted pigeon pox vaccine (TCAPPV), and the second was vaccinated with egg adapted pigeon pox vaccine (EAPPV) and the third as a nonvaccinated control group. Birds were observed for ten days postvaccination (DPV) for the presence of takes. Cellular immunity was detected by lymphocyte proliferation assay on the whole blood for 21 DPV, and serum samples were collected
... s were collected weekly. The level of induced antibodies was detected by the neutralization test for six months postvaccination. Twenty pigeons of each group were challenged by virulent pp virus at 28 th DPV Takes were recognized at the site of vaccination at 4 th DPV and increased to the maximum at7 th DPV to reach 90% for TCAPPV and 98% for EAPPV. The peak of the cellular immunity by lymphocyte proliferation assay was at the 12 th DPV when TCAPPV recorded 1.534 and EAPPV 2.037. Protection was 90% for TCAPPV and 100% for EAPPV. The peak of neutralizing index (NI) at 35 th D.P.V for both vaccinated groups; It was 2.75 for TCAPPV and 3.25 for EAPPV. Both vaccines are still potent to the end of examination at the 6 th month when NI was 1.5 for TCAPPV and 2.0 for EAPPV. This result shows that both eggs adapted PP and tissue culture PP vaccines are efficient in the protection of pigeons in Egypt despite the egg adapted vaccine is more preferable. ـــــــــــــــــــــــــــــــــــــــــ This is an open access article under the term of the Creative Commons Attribution 4.0 (CC-BY) International License . To view a copy of this license, visit http://creativecommons.org/licenses/by/ 4.0/ J. Appl. Vet. Sci., 5(2 ): 87-93.