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CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR- associated nuclease 9) provides powerful gene-editing tools that are applicable for gene therapy of a variety of diseases including, but not limited to cancer, rare diseases, and heart disease. In the current study, we first examined our artificial stem cell and organoid models that were generated by our literature validated DeepNEU platform from the perspective of gene-editing. We then evaluated the aiCRISPRLdoi:10.1101/2022.06.18.496679 fatcat:h3wpgaemyneapjxgk3fbqqayvm