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Enzymes are increasingly being used in an industrial setting as a cheap and environmentallyfriendly alternative to chemical catalysts. In order to produce the ideal biocatalyst, natural enzymes often require optimization to increase their catalytic efficiencies and specificities under a particular range of reaction conditions. A number of enzyme engineering strategies are currently employed to modify biocatalysts, improving their suitability for large-scale industrial applications. Thesedoi:10.1021/cs200217t pmid:22125758 pmcid:PMC3224019 fatcat:e3lzfwud5bcdha5riewcx3pa3a