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This study aimed to evaluate the effectiveness of Calvital ® , which is a calcium hydroxide formulation, on persistent apical periodontitis caused by over-enlargement of the apical foramen. The study included patients referred to the Department of General Dentistry at Tokyo Dental College Suidobashi Hospital on a diagnosis of persistent apical periodontitis at an external dental clinic. Of them, 20 showing considerable enlargement of the apical foramina were included in the study. Completedoi:10.2209/tdcpublication.52.209 pmid:22293591 fatcat:6vskjd2h3jes7pem23cqbagwkq