Dr Haider Iftikhar, Dr Tooba Qaiser, Dr Shafaq Mussadiq
2020 Zenodo  
Hypoalbuminemia is an important risk factor for the development of hypotension during hemodialysis and progressive left ventricular hypertrophy in patients with chronic kidney disease (CKD). Aim: The aim of the study was to evaluate the relationship between serum albumin, intradialysis hypotension (IDH) and cardiac function. Place and Duration: In the Nephrology and Cardiology department of Nishtar Hospital Multan for one-year duration from August 2019 to 2020. Patients and Methods: Forty
more » ... ts undergoing regular hemodialysis (HD) were enrolled in the study. They were divided into two groups; Group 1: Patients in this group had recurrent attacks of IDH and Group 2: Patients in this group did not develop IDH. Patients were reclassified according to their serum albumin level into two groups; Group A: patients with hypoalbuminemia and group B: patients without hypoalbuminemia. Data collected from each patient included: (1) demographic characteristics (age, gender) and clinical characteristics (changes in blood pressure during the session, ultrafiltration index, cardio-thoracic ratio, duration of dialysis and Kt / V); (2) Blood chemistry (creatinine, urea, hemoglobin, hematocrit value, total proteins, albumin, triglycerides, cholesterol, AST, ALT, Kt / V and fasting blood sugar); and (3) Echocardiographic evaluation of left ventricular geometry. Results: There was a significant negative correlation between serum albumin and Delta BP in HD patients. There were also no significant changes in heart function in the various groups studied. Conclusion: We concluded that there is an association between low serum albumin and intradialysis hypotension and cardiac function in patients with CKD undergoing HD. Recommendations: Regular serum albumin testing is mandatory for all HD patients. Key words [...]
doi:10.5281/zenodo.4314149 fatcat:lozw5roqajagfgylwts267avou