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Reconstruction of highly heterogeneous gene-content evolution across the three domains of life
2007
Computer applications in the biosciences : CABIOS
Motivation: Reconstruction of gene-content evolutionary history is fundamental in studying the evolution of genomes and biological systems. To reconstruct plausible evolutionary history, rates of gene gain/loss should be estimated by considering the high level of heterogeneity: e.g. genome duplication and parasitization, respectively, result in high rates of gene gain and loss. Gene-content evolution reconstruction methods that consider this heterogeneity and that are both effective in
doi:10.1093/bioinformatics/btm165
pmid:17646301
fatcat:ckhrjy4udjb7nf3ww45djpmmqy