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Clinicopathological Effect of Induced Pluripotent stem cells and Hormonal Therapy on Premature Ovarian Failure
Benha veterinary medical journal
This experiment was designed to investigate the roles of induced pluripotent stem cells and hormonal therapy on experimentally-induced ovarian ablation (OA) by evaluating of hormonal (E2, FSH, LH), molecular (Oct4, Runx2, Stra8), histopathological (H&E) and immunohistochemical (PCNA) examinations. Fifty female rats were classified into five main groups. Group (I): 10 rats as control normal group. Group II (OA):10 rats infused with (3 mg/kg) of DOX and (50 mg) CYP dissolved in cleandoi:10.21608/bvmj.2021.66527.1352 fatcat:f4723dtdszgive3yjx5apre4cy