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Haematopoietic stem cells and mesenchymal stem cells as tools for present and future cellular therapies
Swiss Medical Weekly
Postnatal stem cells are present in many adult tissues, and are thought to ensure homoeostasis by replacing functionally declining cells by newly differentiated ones. Postnatal stem cells used as such or after in vitro manipulation hold out strong hopes for reconstructive therapies. For instance, the grafting of native haematopoietic stem cells (HSC) restores haematopoiesis in genetically deficient individuals or in lethally conditioned leukaemic patients, and systemic injection of in vitropmid:16826633 fatcat:bp4owo7ld5aizir6zxzo7xkeoq