Feline Infectious Peritonitis: Challenges and Promises of Coronavirus RNA Detection [post]

Wadim Kapulkin, Pawel Kita
2020 unpublished
Our perspective article covers major findings concerning Feline Infectious Peritonitis (FIP) - a fatal coronaviral disease of cats. In the context of FIP pathogenesis, we outline disease signalment and focus on the challenges and promises of FIP invoking coronavirus RNA detection. In particular, we outline critical aspects of coronavirus RNA replication and biogenesis. We infer the replicative intermediates of feline coronavirus may constitute an underappreciated factor triggering the
more » ... ering the progression of the maladaptive immune response underlying FIP pathogenesis.
doi:10.20944/preprints202012.0337.v1 fatcat:a6ldvdwpjrcjroaemvaodavrkq