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Malalignment of Total Knee Replacement prosthesis has been reported to limit the implant survival time. We hypothesized that this may be secondary to excessive stress occurring at the bone-implant interface, resulting from abnormal load transfer across the knee joint. In this study, we conducted Finite Element Analysis of a geometrical model of the knee joint after Total Knee Replacement with different axial alignments. The calculated stresses and displacements were significantly higher withpmid:19385508 fatcat:hpvdc7hmuvdpnbwnqbrw4vb3li