Pulmonary embolism – A persisant dilemma

Ranjan Modi, S.V. Patted, P.C. Halkati, S.C. Porwal, Sameer Ambar
2014 Indian Heart Journal  
Prevalence of acute pulmonary embolism is increasing in general population especially in old population. Prevalence of acute pulmonary embolism in young adults is unknown.The objective of this study was to assess the prevalence of acute pulmonary embolism in young (<40 years) population and to compare the clinical presentation and the therapeutic benefit in regards to age at presentation. Settings: A single tertiary cardiac care centre. Methods: In this study, among 202 patients enrolled, 97 &
more » ... nts enrolled, 97 & 105 patients were admitted as young & old patient, respectively. The clinical presentation and course after therapy among them were observed and compared. Results: forty-eight percent of our study population belongs to <40 years of age. There were no significant differences seen in functional class, hypotension, electrocardiographic & echocardiographic features based on age difference. Clinical improvement after treatment (68% vs 78%, p¼0.42) and in hospital death (10% vs 16%, p¼0.36) was non-significantly more in older than in young patients. Though the incidence of minor bleeding (14% vs 11%, p¼0.68) was non-significantly higher in older group of patients but two patients in this group had intra-cerebral bleed following thrombolytic therapy. Conclusion: As there were no significant differences in the clinical presentation, therapeutic benefit, and course after therapy and complication, therefore, age should not influence the decision to treat pulmonary embolism patients especially with thrombolytic agents though caution should be taken while treating older patients. Background: In hypothyroidism there is reduced production of
doi:10.1016/j.ihj.2014.10.330 fatcat:yzlwqj3nbjhnhdtznf4sal2jxq