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The emergence and rapid global spread of SARS-CoV-2 mark the third such identification of a novel corona- virus capable of causing severe, potentially fatal disease in humans in the 21st century. As noted by Andersen et al. (Nature Medicine), the sequencing of proximal zoonotic ancestors to SARS-CoV-2 has aided in the iden- tification of alleles that may contribute to the virus' virulence in humans.doi:10.17615/9pss-8944 fatcat:hr3zrszz7jahbgezw322muotkq