Gender differences in systemic sclerosis: relationship to clinical features, serologic status and outcomes

Christine Peoples, Thomas A. Medsger, Mary Lucas, Bedda L. Rosario, Carol A. Feghali-Bostwick
2016 Journal of Scleroderma and Related Disorders  
Introduction-There is a strong female preponderance reported in many connective tissue diseases and in almost all systemic sclerosis (SSc) case series. Methods-We compared gender differences in SSc patients in a large single-center cohort, including demographic features, disease subtype, environmental exposures, disease-specific serum autoantibodies, organ system involvement (frequency and severity) and survival. Adjustment for cutaneous subset (diffuse cutaneous [dc] and limited cutaneous [lc]) was performed.
doi:10.5301/jsrd.5000209 pmid:29242839 pmcid:PMC5726425 fatcat:aymujex24bfsbpu5yl33jvnkbi