THEORETICAL AND EXPERIMENTAL INVESTIGATION OF PYRIDYL-THIOUREA DERIVATIVES AS IONOPHORES FOR Cu(II) ION DETECTION

Wan M. Khairul, Mohd Faizuddin Abu Hasan, Adibah Izzati Daud, Hafiza Mohamed Zuki, Ku Halim Ku Bulat, Maisara Abdul Kadir
2016 Malaysian Journal of Analytical Science  
Copper (II) ion chemical sensors based on pyridine-thiourea derivatives; N-pyridyl-N'-(biphenyl-4-carbonyl)thiourea (L1), and N-pyridyl-N'-(3,5-dimethyoxybenzoyl)thiourea (L2) were synthesised, characterised, and studied as ionophores in the form of thin-films PVC membranes. The ionophores exhibited good responses towards copper (II) ion over the concentration range of 2 x 10 -4 to 10 x 10 -4 M with a limit of detection 1.34 x 10 -5 to 1.48 x 10 -5 M. The proposed sensors L1 and L2 revealed
more » ... and L2 revealed good performance in term of reproducibility and regeneration of the ionophores with low relative standard deviation (RSD) values 4.17 % and 2.74 % respectively. Besides, quantum chemical calculation performed using Gaussian 09 program indicated the oxygen (O) atom from carbonyl moiety (C=O) was the most favourite reactive site and mainly responsible for ionophore-Cu(II) interaction. The obtained data revealed pyridine-thiourea derivatives offered great potential as ionophore for the detection of Cu (II) ion.
doi:10.17576/mjas-2016-2001-08 fatcat:rkyhprln6vbjhidgjvdue5by5u