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Detection of PIK3R1 (L449S) Mutation in a Patient with Ovarian Cancer: A Case Report
2020
Case Reports in Oncology
Ovarian cancer (OC) is one of the most dangerous gynecological diseases and greatly increases the death risk worldwide. The heterogeneity of the ovarian tumors among patients and the lack of sufficient therapies for these tumors make the selection of the appropriate treatment a hard challenge. Understanding the mechanisms leading to OC becomes an urgent need in order to find out better therapeutic strategies. In this study, we have identified a point mutation (L449S) in the regulatory subunit
doi:10.1159/000505723
pmid:32231543
pmcid:PMC7098360
fatcat:6lvwx52d5failgvhs5w4fuhmsq